Muscle wasting parameters
| Ctrl (n=5) | NASH (n=9) | NASH-resv (n=9) | NASH-resv+EX527 (n=9) | |
| Body weight (g) | 24.6±49 | 39.8±3.1* | 32.4±2.4 | 36.1±2.7 |
| Whole forelimb muscle weight (μg) | 173.7±8.9 | 89.1±2.9* | 117.2±4.8† | 104.2±3.1 |
| Whole hindlimb muscle weight (μg) | 246.8±3.2 | 127.7±6.3** | 167.5±3.1† | 148.3±2.6 |
Forelimb muscles are including bilateral quadriceps, deltoid, triceps, and biceps; hindlimb muscles are including bilateral T, gastrocnemius, solues, and plantaris.
†p<0.05 vs NASH-group.
*, **p<0.05, 0.01 vs Ctrl-group.
NASH, non-alcoholic steatohepatitis.