Participant demographics
| NBDO n=306 | DBO n=49 | GORD n=132 | Colonic polyp n=152 | Healthy n=48 | ||
| Age (years) | Mean | 64.6 | 71 | 60.9 | 68.6 | 50.3 |
| Range | 26–85 | 55–84 | 30–90 | 48–89 | 20–80 | |
| Sex | Male | 198 | 44 | 72 | 100 | 24 |
| Female | 108 | 5 | 60 | 52 | 23 | |
| % male | 64.70% | 89.80% | 60.90% | 65.80% | 51.10% | |
| Employment status | Employed | 32.70% | 8.20% | 35.90% | 17.30% | 85.10% |
| Unemployed | 6.70% | 0.00% | 10.90% | 2.70% | 4.30% | |
| Retired | 60.60% | 91.80% | 53.10% | 80.00% | 10.60% | |
| Family history | Cancer | 20.60% | 24.50% | 27.80% | 16.90% | 50.00% |
| Disease specific cancer | 7.2% (OAC) | 2% (OAC) | 5.4% (OAC) | 22.5% (CRC) | NA | |
| Chronic disease | 15.40% | 16.30% | 21.50% | 13.90% | 33.30% | |
| Carer | Yes | 6.90% | 14% | 13.20% | 11.30% | 2.10% |
| Smoking | Never | 43.30% | 26.50% | 49.60% | 39.70% | 70.80% |
| Current | 11.10% | 4.10% | 11.60% | 10.60% | 8.30% | |
| Ex-smoker | 45.60% | 69.40% | 38.80% | 49.70% | 20.80% | |
| PPI usage | Yes | 95.10% | 100.00% | 84.60% | 45.70% | 0.00% |
| Antidepressant usage | Yes | 8.50% | 10.20% | 18.30% | 10.60% | 0.00% |
| Prague M classification | Mean | 3.6 | 3.9 | NA | NA | NA |
| Comorbidity prevalence | None | 29.40% | 14.30% | 25.00% | 21.70% | 100.00% |
| 1–2 | 54.20% | 59.20% | 55.30% | 57.90% | 0% | |
| 3–4 | 16.00% | 22.40% | 17.40% | 17.10% | 0% | |
| >4 | 0.30% | 4.10% | 2.30% | 3.30% | 0% |
CRC, colorectal cancer; DBO, dysplastic Barrett’s oesophagus; GORD, gastro-oesophageal reflux disease; NDBO, non-dysplastic Barrett’s oesophagus; OAC, oesophageal adenocarcinoma; PPI, proton pump inhibitor.