Table 4

The adjusted hazard risk of individuals with or without NAFLD and obesity for incident gastric cancer or colorectal cancer

	HR (95% CI)	P value	HR (95% CI)	P value
Incident gastric cancer	Model 1		Model 2
Non-NAFLD without obesity	Ref		Ref
NAFLD without obesity	1.96 (0.86 to 4.47)	0.11	1.84 (0.8 to 4.23)	0.15
Non-NAFLD with obesity	0.88 (0.21 to 3.73)	0.86	0.86 (0.2 to 3.67)	0.84
NAFLD with obesity	3.58 (1.73 to 7.38)	0.001	3.3 (1.57 to 6.9)	0.002
Exerciser	1.00 (0.48 to 2.10)	1.00	1.01 (0.48 to 2.13)	0.97
Alcohol consumption	1.00 (0.99 to 1.00)	0.6	1 (0.99 to 1)	0.59
Male	0.7 (0.31 to 1.6)	0.4	0.69 (0.3 to 1.57)	0.37
Age	1.13 (1.1 to 1.17)	＜0.001	1.13 (1.1 to 1.17)	0
Never smoker	Ref		Ref
Ex-smoker	1.64 (0.67 to 4.01)	0.28	1.65 (0.68 to 4.03)	0.27
Current smoker	2.71 (1.2 to 6.11)	0.016	2.75 (1.22 to 6.19)	0.014
Diabetes			2.19 (0.76 to 6.31)	0.15
Incident colorectal cancer	Model 1		Model 2
Non-NAFLD without obesity	Ref		Ref
NAFLD without obesity	0.98 (0.33 to 2.88)	0.97	0.99 (0.34 to 2.93)	0.99
Non-NAFLD with obesity	1.96 (0.74 to 5.17)	0.17	1.97 (0.75 to 5.2)	0.17
NAFLD with obesity	2.96 (1.44 to 6.09)	0.003	3.04 (1.47 to 6.3)	0.003
Exerciser	0.83 (0.37 to 1.89)	0.66	0.83 (0.37 to 1.88)	0.66
Alcohol consumption	1 (1 to 1.01)	0.12	1 (1 to 1.01)	0.12
Male	1.33 (0.57 to 3.14)	0.51	1.34 (0.57 to 3.15)	0.5
Age	1.04 (1 to 1.07)	0.053	1.04 (1 to 1.07)	0.049
Never smoker	Ref		Ref
Ex smoker	1.40 (0.62 to 3.15)	0.42	1.39 (0.62 to 3.14)	0.43
Current smoker	1.33 (0.6 to 2.94)	0.48	1.33 (0.6 to 2.93)	0.49
Diabetes			0.64 (0.09 to 4.81)	0.67

The HRs of the four group for incident gastric cancer and colorectal cancer are calculated by the Cox proportional hazards model. In model 1, exerciser, alcohol consumption, male, age, smoking sates are used as covariates. In addition to them, diabetes is used as a covariate in model 2.
NAFLD, non-alcoholic fatty liver disease.