Outcome/FLI category | Model 1 HRs (95% CI) | Model 2 HRs (95% CI) | Model 3 HRs (95% CI) | |
All-cause mortality | ||||
≤30 (Ref.) | 295 | 1.00 | 1.00 | 1.00 |
30–<60 | 217 | 1.16 (0.97 to 1.39) | 1.08 (0.90 to 1.29) | 0.97 (0.80 to 1.18) |
≥60 | 188 | 1.65 (1.37 to 1.99) | 1.47 (1.21 to 1.78) | 1.10 (0.87 to 1.39)* |
P trend | <0.001 | <0.001 | 0.51 | |
Disease mortality | ||||
≤30 (Ref.) | 270 | 1.00 | 1.00 | 1.00 |
30–<60 | 204 | 1.19 (0.99 to 1.43) | 1.10 (0.92 to 1.33) | 0.98 (0.81 to 1.20) |
≥60 | 177 | 1.71 (1.41 to 2.08) | 1.52 (1.25 to 1.85) | 1.11 (0.87 to 1.42) |
P trend | <0.001 | <0.001 | 0.48 | |
CVD mortality | ||||
≤30 (Ref.) | 138 | 1.00 | 1.00 | 1.00 |
30–<60 | 105 | 1.19 (0.92 to 1.54) | 1.09 (0.84 to 1.41) | 0.91 (0.69 to 1.20) |
≥60 | 96 | 1.62 (1.24 to 2.12) | 1.43 (1.09 to 1.88) | 0.89 (0.63 to 1.25)† |
P trend | 0.001 | 0.01 | 0.47 | |
Non-CVD mortality | ||||
≤30 (Ref.) | 157 | 1.00 | 1.00 | 1.00 |
30–<60 | 112 | 1.14 (0.89 to 1.45) | 1.08 (0.84 to 1.38) | 1.08 (0.83 to 1.41) |
≥60 | 92 | 1.55 (1.19 to 2.02) | 1.42 (1.08 to 1.85) | 1.33 (0.96 to 1.86)‡ |
P trend | 0.002 | 0.02 | 0.11 | |
Cancer mortality | ||||
≤30 (Ref.) | 76 | 1.00 | 1.00 | 1.00 |
30–<60 | 59 | 1.21 (0.86 to 1.71) | 1.15 (0.82 to 1.64) | 1.13 (0.78 to 1.64) |
≥60 | 42 | 1.43 (0.98 to 2.10) | 1.31 (0.89 to 1.94) | 1.21 (0.75 to 1.98)§ |
P trend | 0.06 | 0.17 | 0.42 |
Model 1: FLI category, examination date, age, family history of diabetes, family history of cardiovascular disease, smoking status, alcohol consumption, physical activity, fruit, berry & berry consumption (and CVD history for CVD mortality) (and cancer history for cancer mortality).
Model 2: Model 1 plus C reactive protein, fibrinogen, leucocytes and thrombocytes.
Model 3: Model 2 plus systolic blood pressure, diastolic blood pressure, insulin, fasting glucose, LDL, HDL.
*All-cause mortality: Other independent predictors were age, smoking pack years, alcohol consumption, fibrinogen, leucocyte count, systolic blood pressure and glucose.
†CVD mortality: Other independent predictors were age, smoking pack years, alcohol consumption, fibrinogen, leucocyte count, systolic blood pressure and glucose.
‡Non-CVD mortality: Other independent predictors were age, smoking pack years, alcohol consumption, leucocyte count and glucose.
§Cancer mortality: Other independent predictors were age, smoking pack years and thrombocyte count.
¶Disease mortality: Other independent predictors were age, smoking packyears, alcohol consumption, fibrinogen, leucocyte count, systolic blood pressure and glucose.
**Statistically significant at p≤0.05.
CVD, cardiovascular disease; FLI, fatty liver index; Ref, reference.