Factors associated with postoperative clinical outcomes of fistula surgery
| Factors | Healed (n=207) | Failed (n=132) | OR (95% CI) | P-value |
| Gender (M:F) | 172:35 | 114:18 | 0.77 (0.42 to 1.44) | 0.419 |
| Age (mean±SD) (years) | 43.2±13.4 | 40.8±12.6 | 0.99 (0.97 to 1.00) | 0.986 |
| Underlying diseases | ||||
| Diabetes mellitus | 18 | 8 | 1.48 (0.62 to 3.50) | 0.376 |
| HIV infection | 20 | 10 | 1.31 (0.59 to 2.88) | 0.511 |
| Pulmonary tuberculosis | 20 | 3 | 0.42 (0.07 to 2.55) | 0.345 |
| Dyslipidemia | 2 | 1 | 0.78 (0.07 to 8.72) | 0.842 |
| Fistula types | ||||
| Subcutaneous/intersphincteric | 22/12 | 2/5 | 1.13 (1.00 to 1.27) | 0.061 |
| Low/high transsphincteric | 79/94 | 15/110 | ||
| Fistula classification | ||||
| Simple/complex | 113/94 | 22/110 | 6.01 (3.53 to 10.25) | <0.001* |
| Single/multiple tracts | 182/25 | 126/6 | 0.36 (0.16 to 0.83) | 0.016* |
| Recurrent cases | 27 | 32 | 0.47 (0.27 to 0.83) | 0.009* |
| Mean no of previous surgeries | 0.6 (0–8) | 1.0 (0–10) | 1.32 (1.08 to 1.62) | 0.008* |
| Preoperative imaging | ||||
| Preoperative EAUS | 69 | 40 | 1.15 (0.72 to 1.84) | 0.560 |
| EAUS-Op concordance | 61 | 36 | 0.65 (0.16 to 2.55) | 0.522 |
| Operations | ||||
| LIFT/ARP | 77/1 | 84/1 | 0.56 (0.46 to 0.70) | <0.001* |
| Fistulotomy/HF Fistulectomy/core-out F | 114/2 1/6 | 27/2 1/2 | ||
| Drainage | 6 | 15 | ||
| Follow-up time (weeks) | 29.5±26.8 | 40.0±29.8 | 1.01 (1.01 to 1.02) | 0.001* |
*p<0.05.
ARP, anorectal advancement flap;EAUS, endoanal ultrasound; Core-out F, core-out fistulectomy;HF, Hanley’s fistulotomy;LIFT, ligation of intersphincteric fistula tract;Op, operative finding; SPO, sphincter-preserving operation.