Table 2

Prevalence of opioid and benzodiazepine prescription by chronic disease

CategoryCirrhosisHepatitis C without cirrhosisCHFCOPDP value
All
 Number of patients169 181210 191766 8401 438 798
 Person-years294 692456 3631 811 1063 716 909
Opioids
 Number of patients using opioids 2009–2015109 444113 486470 956902 192
 Prevalence of opioid prescription per 100 person-years (95% CI)37.1 (37.0 to 37.3)24.9 (24.7 to 25.0)26.0 (25.9 to 26.1)24.3 (24.2 to 24.3)<0.001
Benzodiazepine
 Number of patients using benzodiazepine 2009–201562 70356 036219 258478 494
 Prevalence of benzodiazepine per 100 person-years (95% CI)21.3 (21.1 to 21.4)12.3 (12.2 to 12.4)12.1 (12.1 to 12.2)12.9 (12.8 to 12.9)<0.001
Both opioids and benzodiazepines
 Number of patients using both opioids and benzodiazepine 2009–201551 47543 948175 153390 820
 Prevalence of both opioid and benzodiazepine per 100 person-years (95% CI)17.5 (17.3 to 17.6)9.6 (9.5 to 9.7)9.7 (9.6 to 9.7)10.5 (10.5 to 10.5)<0.001
  • CHF, congestive heart failure;COPD, chronic obstructive pulmonary disease.