Table 3

Beta-diversity analysis comparing obese and non-obese within cases and controls

TypeReference (Sample)UniFracGUniFracWUniFracBray-CurtisJaccardOmnibus test
F P value F P value F P value F P value F P valueP value
16S rRNA Baxter et al 11 (Stool)
Non-CRC-Ob vs Non-Ob 1.852 0.011 1.871 0.027 1.7980.111 1.792 0.019 0.024
CRC-Ob vs Non-Ob 1.1560.1751.2210.1790.8970.4221.4520.0690.136
Zackular et al 6 (Stool)
Non-CRC-Ob vs Non-Ob 1.3140.088 1.784 0.022 2.824 0.007 1.494 0.054 0.015
CRC-Ob vs Non-Ob 1.1910.1661.4790.0932.1830.0501.3680.0940.117
Zeller et al (Stool)
Non-CRC-Ob vs Non-Ob 1.691 0.006 1.565 0.040 1.3870.1801.3930.101 0.014
CRC-Ob vs Non-Ob 1.1320.2081.1270.2801.3940.1781.1420.2760.327
Zeller et al (Tissue)
Non-CRC-Ob vs Non-Ob 1.1590.1891.4110.0601.5960.095 1.597 0.027 0.066
CRC-Ob vs Non-Ob 1.3530.0561.1250.2750.8800.5481.1060.3070.136
WGS Vogtmann et al (Stool)
Non-CRC-Ob vs Non-Ob 0.8970.4851.0410.4220.508
CRC-Ob vs Non-Ob 1.0860.3571.0680.3550.426
Feng et al 10 (Stool)
Non-CRC-Ob vs Non-Ob 3.129 0.003 4.144 0.008 0.004
CRC-Ob vs Non-Ob 2.923 0.019 4.972 0.008 0.010
Zeller et al (Stool)
Non-CRC-Ob vs Non-Ob 1.8210.081 2.892 0.047 0.065
CRC-Ob vs Non-Ob 1.0250.3820.9720.4240.461
  • F values from PERMANOVA testing on single or multiple distance metrics (omnibus test).

  • Values in bold are significant at p<0.05.

  • CRC, colorectal cancer.