Table 1

Diagnostic accuracy of the methods for diagnosing a CMV colitis in the IBD cohort

Diagnostic method for CMV detectionSensitivity (%)Specificity (%)PPV (%)NPV (%)
CMV-DNA-PCR from serum (n=47)6510010079
CMV-DNA-PCR of TS (n=47)7010010082
CMV-DNA-PCR >250 copies/mg of TS (n=11)79839263
Owl eyes in H&E of TS (n=47)0100070
IHC of TS (n=47)1410010073
  • CMV, cytomegalovirus; IBD, inflammatory bowel disease; IHC, immunohistochemistry; NPV, negative predictive value;PPV, positive predictive value;TS, tissue sample.