Diagnostic method for CMV detection | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) |
CMV-DNA-PCR from serum (n=61) | 80 | 57 | 46 | 85 |
CMV-DNA-PCR of TS (n=61) | 80 | 100 | 100 | 91 |
CMV-DNA-PCR >250 copies/mg of TS (n=11) | 92 | 88 | 92 | 88 |
Owl eyes in H&E of TS (n=61) | 5 | 96 | 50 | 37 |
IHC of TS (n=61) | 5 | 100 | 100 | 38 |
CMV, cytomegalovirus; HSCT, haematopoietic stem cell transplantation; IHC, immunohistochemistry; NPV, negative predictive value; PPV, positive predictive value; TS, tissue sample.