Table 1

Diagnostic procedures and results obtained

03/2016GastroscopyHP-positive chronic gastritis type A
CT thoraxLymph nodes of a maximum diameter of 1 cm, subpleural consolidations
CT abdomenDysontogenetic liver cysts
03/29/2016ADAMTS-13 activity5%
ADAMTS-13 antibody66.0 IU/mL
ANCA, dsDNA, C3, C4, Rheumatoid factorNegative
ANAPositive without specific subtype
HIT 2 ELISANegative
03/29/2016Hepatitis B serology (HBV-Surface-AG, HBV-Core-Ab)Negative
Hepatitis C serologyNegative
HIV serologyNegative
CMV serologyIgM negative, IgG 140 IU/mL
VZV serologyNegative
HSV serologyNegative
Parvovirus B19 serologyNegative
03/30/2016Stool PCR for Astrovirus, Norovirus, Rotavirus, adenovirusNegative
03/31/2016PET CTPleural effusions, bone marrow activity
03/30/2016Stool culture for Shigella, Salmonella, Yersinia, CampylobacterNegative
Stool PCR for Clostridium difficile, E. coli Negative
05/03/2016Serology and PCR for CMVIgM negative, IgG >250 IU/mL, 9960 IU/mL
05/10/2016Biopsy PCR for Tropheryma whipp e l ii Negative
Biopsy immunohistochemistry for Mycobacterium tuberculosisNegative
05/11/2016IntestinoscopySevere enteritis (figure 1D), polyclonal TCR pattern: no T-Cell Lymphoma
05/18/2016Blood PCR for CMVNegative
05/26/2016MRI SellinkUbiquitary enhancement of contrast agent in stomach and small intestine with maximum in jejunal part (figure 1A,B)
06/08/2016Blood PCR for CMV10 400 IU/mL
06/15/2016Blood PCR for CMVNegative
07/25/2016HLA DQ2Negative
HLA DQ8Negative
09/14/2016IntestinoscopySevere enteritis
09/18/2016cMRIOedema of the thalamic area
09/22/2016Aspirate and trepanateHypocellular bone marrow aspirate due to azathioprin toxicity, normocellular bone marrow trapanate
Blood PCR for CMV9 IU/mL
09/27/2016Autoimmune encephalitisNegative
09/30/2016Blood PCR for CMV578 IU/mL
10/06/2016Blood PCR for CMVNegative
10/25/2016IntestinoscopySevere enteritis with new stenosis 120 cm aboral (figure 1E)
12/12/2016IntestinoscopyReduction of known subtotal stenosis decreasing sign of inflammation (figure 1G)
  • ANA, anti-nuclear autoantibodies; ANCA, anti-neutrophilic cytoplasmic autoantibodies; CMV, cytomegalovirus; HLA, human leukocyte antigen; HSV, herpes simplex virus; SLE, systemic lupus erythematodes; VZV, varicella zoster virus; vWF, von-Willebrand factor.