TY - JOUR T1 - Quality of life in patients with IBD during the COVID-19 pandemic in the Netherlands JF - BMJ Open Gastroenterology JO - BMJ Open Gastro DO - 10.1136/bmjgast-2021-000670 VL - 8 IS - 1 SP - e000670 AU - Ellen de Bock AU - Mando D Filipe AU - Vincent Meij AU - Bas Oldenburg AU - Fiona D M van Schaik AU - Okan W Bastian AU - Herma F Fidder AU - Menno R Vriens AU - Milan C Richir Y1 - 2021/07/01 UR - http://bmjopengastro.bmj.com//content/8/1/e000670.abstract N2 - Objective COVID-19 has put a strain on regular healthcare worldwide. For inflammatory bowel disease (IBD), gastrointestinal surgeries were postponed and changes in treatment and diagnostic procedures were made. As abrupt changes in treatment regimens may result in an increased morbidity and consequent well-being of patients with IBD, the aim of this study was to determine the effect of the COVID-19 pandemic on health-related quality of life (HRQoL) in patients with IBD.Design All patients with IBD who completed both Inflammatory Bowel Disease Questionnaire (IBDQ) and 36-Item Short Form Health Survey (SF-36) questionnaire between 31 August and 13 September 2020 were included in our cohort study. The primary end point was to determine the HRQoL in patients with IBD, measured by the IBDQ and SF-36 questionnaire. The secondary end point was determining which factors influence the HRQoL in patients with IBD.Results 582 patients with IBD filled in the IBDQ and SF-36 questionnaire. The HRQoL in our study population was low according to the questionnaires on both physical and mental subscales. In addition, multivariate analysis showed that increased age, female sex and patients who underwent surgery had a significantly lower HRQoL, most frequently on the physical domains in both questionnaires.Conclusion Patients with IBD had an overall low HRQoL during the COVID-19 pandemic. Furthermore, older patients, women and patients who underwent surgical procedures had the lowest physical HRQoL.Data are available upon reasonable request. ER -