RT Journal Article SR Electronic T1 Consensus for the management of pancreatic exocrine insufficiency: UK practical guidelines JF BMJ Open Gastroenterology JO BMJ Open Gastro FD BMJ Publishing Group Ltd SP e000643 DO 10.1136/bmjgast-2021-000643 VO 8 IS 1 A1 Mary E Phillips A1 Andrew D Hopper A1 John S Leeds A1 Keith J Roberts A1 Laura McGeeney A1 Sinead N Duggan A1 Rajesh Kumar YR 2021 UL http://bmjopengastro.bmj.com//content/8/1/e000643.abstract AB Introduction Pancreatic exocrine insufficiency is a finding in many conditions, predominantly affecting those with chronic pancreatitis, pancreatic cancer and acute necrotising pancreatitis. Patients with pancreatic exocrine insufficiency can experience gastrointestinal symptoms, maldigestion, malnutrition and adverse effects on quality of life and even survival.There is a need for readily accessible, pragmatic advice for healthcare professionals on the management of pancreatic exocrine insufficiency.Methods and analysis A review of the literature was conducted by a multidisciplinary panel of experts in pancreatology, and recommendations for clinical practice were produced and the strength of the evidence graded. Consensus voting by 48 pancreatic specialists from across the UK took place at the 2019 Annual Meeting of the Pancreatic Society of Great Britain and Ireland annual scientific meeting.Results Recommendations for clinical practice in the diagnosis, initial management, patient education and long term follow up were developed. All recommendations achieved over 85% consensus and are included within these comprehensive guidelines.Data sharing not applicable as no datasets generated and/or analysed for this study. Not applicable.