PT - JOURNAL ARTICLE AU - Giacomo Caio AU - Lisa Lungaro AU - Fabio Caputo AU - Maria Muccinelli AU - Maria Caterina Marcello AU - Eleonora Zoli AU - Umberto Volta AU - Roberto De Giorgio AU - Giorgio Zoli TI - Recurrent myocarditis in a patient with active ulcerative colitis: a case report and review of the literature AID - 10.1136/bmjgast-2020-000587 DP - 2021 Mar 01 TA - BMJ Open Gastroenterology PG - e000587 VI - 8 IP - 1 4099 - http://bmjopengastro.bmj.com//content/8/1/e000587.short 4100 - http://bmjopengastro.bmj.com//content/8/1/e000587.full SO - BMJ Open Gastro2021 Mar 01; 8 AB - Inflammatory bowel diseases such as ulcerative colitis (UC) may be complicated by several extraintestinal manifestations. These involve joints, skin, eyes and less commonly lungs and heart. Myocarditis may result from the toxic effect of drugs (ie, mesalazine) commonly used for the treatment of UC or due to infections (eg, Coxsackieviruses, enteroviruses, adenovirus). Here, we report a case of a 26-year old man affected by UC and complicated by two episodes of myocarditis. Both episodes occurred during two severe exacerbations of UC. However, in both cases the aetiology of myocarditis remains uncertain being ascribable to extraintestinal manifestation, drug toxicity or both.