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Adenoma Detection before and after the age of 50: a retrospective analysis of Lebanese outpatients
  1. Mohammed Hussein Kamareddine1,
  2. Youssef Ghosn1,
  3. Karam Karam1,
  4. Anwar Andrew Nader1,
  5. Ahmad El-Mahmoud1,
  6. Naseem Bou-Ayash1,
  7. Mansour El-Khoury2,
  8. Said Farhat3
  1. 1Department of Medicine and Medical Sciences, University of Balamand, El-Koura, Lebanon
  2. 2Department of General Surgery, Saint George Hospital University Medical Center, Beirut, Lebanon
  3. 3Department of Gastroenterology, Saint George Hospital University Medical Center, Beirut, Lebanon
  1. Correspondence to Dr Said Farhat; Saidfarhat{at}hotmail.com

Abstract

Background and aim Colorectal cancer (CRC) has an increased impact on the Lebanese population’s morbidity and mortality. This study evaluated the situation of adenoma detection in an outpatient clinic in Lebanon.

Patients and methods 918 patients underwent colonoscopy over a period of 24 months by a qualified physician. Biopsy results were divided into normal versus abnormal colonic tissue, which was further subdivided into number of polyps and cancer.

Results Out of 918 individuals included, 82 cases of Crohn’s colitis (8.93%) and 22 cases of ulcerative colitis (2.39%) were identified. A total of 42 cases of CRC (4.58%) and 188 cases of adenomatous polyps (20.48%) were identified. The data show that age >50 years and male gender significantly correlate with increased incidence of precancerous and cancerous polyps. Further exploring the results by age groups and gender, detection of adenomatous polyps in women aged 40–49 (8.33%) was significantly different from their female counterparts aged ≥50 years old (25.26%) (p<0.01). However, no statistical difference between detection of adenomas was found between men aged 40–49 (33.33%) and their male counterparts aged ≥50 years old (37.5%) (p=0.6).

Conclusion Within the limitations of this study, the incidence of CRC and adenomatous polyps falls in the high range compared with international studies. Furthermore, symptomatic male patients aged 40–49 appear to exhibit detection rates of adenomas similar to their counterparts aged ≥50 years old. Subjects younger than 50 years underwent diagnostic rather than screening colonoscopy, which introduces some selection bias. Nevertheless, these findings can serve as a basis for further studies.

  • colon carcinogenesis
  • colonic adenomas
  • colonic neoplasms
  • colonoscopy

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0

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Footnotes

  • Contributors MHK, ME-K and SF conceived of the presented idea. MHK, NB-A, YG, KK and AAN wrote the manuscript. KK, NB-A, AAN and AE-M entered the data. MHK, SF and YG developed the theory and performed the statistical analysis. MHK, ME-K and YG created the tables and figures for the manuscript. SF supervised the project.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Data sharing statement No additional unpublished data are available.

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