Hepatitis C virus genotype 4 (HCV‐4) is the most common variant of the hepatitis C virus
(HCV) in the Middle East and Africa, particularly Egypt. This region has the highest …

METHODS A medical literature search through MEDLINE was conducted using the keyword
“acute hepatitis C” with a variety of keywords focused on (a) epidemiology,(b) natural history …

Hepatitis C virus (HCV) genotypes 4, 5 and 6 represent> 20% of all HCV cases worldwide.
HCV‐4 is mainly seen in Egypt, where it represents 90% of all HCV cases. Antischistosomal …

Background & Aims: Pegylated interferon therapy has not been adequately evaluated in
acute hepatitis C virus (HCV) infection. This randomized trial assessed the efficacy, safety …

Background & Aims: Pegylated interferons (IFNs) with or without ribavirin were shown in
several studies to improve sustained virologic response compared with standard IFN α-2 …

Pegylated interferon α (PEG IFN‐α) improves sustained virological response rates in chronic
hepatitis C, but neither its role in acute hepatitis C nor the biologic basis for its action has …

Serial liver biopsies are the gold standard by which the progression of fibrosis is evaluated.
This longitudinal cohort study assessed the different rates in the progression of fibrosis using …

In patients chronically infected with hepatitis C virus (HCV) genotype 4, the optimum
duration of therapy and the predictors of sustained virologic response (SVR) have not been …

Although colorectal cancer is not a common cancer in Egypt, the age distribution of the
disease shows that a high proportion occurs in children and adults under 40 years of age …

Background & Aims: Immune responses during the first few months of acute hepatitis C virus
(HCV) infection seem crucial for viral control, but the relationship of these responses to …