Background A compelling ethical rationale supports patient engagement in healthcare
research. It is also assumed that patient engagement will lead to research findings that are …

Objective: The aim was to develop clinical practice guidelines on hypertriglyceridemia.
Participants: The Task Force included a chair selected by The Endocrine Society Clinical …

Context: The risks of testosterone therapy in men remain poorly understood. Objective: The
aim of this study was to conduct a systematic review and meta-analyses of testosterone trials …

Objective: The aim was to formulate clinical practice guidelines for pheochromocytoma and
paraganglioma (PPGL). Participants: The Task Force included a chair selected by the …

GRADE suggests that examination of 95% confidence intervals (CIs) provides the optimal
primary approach to decisions regarding imprecision. For practice guidelines, rating down …

Objective: The aim was to formulate clinical practice guidelines for acromegaly. Participants:
The Task Force included a chair selected by the Endocrine Society Clinical Guidelines …

Case reports and case series are uncontrolled study designs known for increased risk of
bias but have profoundly influenced the medical literature and continue to advance our …

Network meta-analysis (NMA), combining direct and indirect comparisons, is increasingly
being used to examine the comparative effectiveness of medical interventions. Minimal …

Purpose: The guideline purpose is to provide the urologist with a framework for the early
detection of prostate cancer in asymptomatic average risk men. Materials and Methods: A …

Importance Five medications have been approved for the management of obesity, but data
on comparative effectiveness are limited. Objective To compare weight loss and adverse …