Original ReportSubcutaneous Methylnaltrexone for Treatment of Opioid-Induced Constipation in Patients With Chronic, Nonmalignant Pain: A Randomized Controlled Study
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Key words
Methylnaltrexone
palliative care
constipation
abdominal pain
opioids
mu-opioid receptor antagonist
opioid-related disorders
chronic disease
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This research was funded by Wyeth Research, which was acquired by Pfizer Inc in October 2009. Pfizer Inc provided funding for writing support, provided by On Assignment Clinical Research, a paid consultant to Pfizer in connection with the development of this manuscript, and for editorial support, provided by Peloton Advantage, LLC. Drs. Schulman, Zhang, Randazzo, and Iyer, Mr. Tzanis, and Ms. Manley are employees of Pfizer Inc. At the time of this study, they were employees of and stockholders in Wyeth.
No author received an honorarium or other form of financial support related to the development of this manuscript.
Copyright © 2011 American Pain Society. Published by Elsevier Inc. All rights reserved.