Clinical study
Malignancy in adult coeliac disease and idiopathic steatorrhoea

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Abstract

From a review of 202 patients with adult coeliac disease (ACD) or idiopathic steatorrhoea (IS) evidence is given that both of these disorders can be complicated by malignancy, either lymphoma or carcinoma of the gastrointestinal tract (especially of the oesophagus). The incidence is highly significant in men, and significant in women. The mean duration of symptoms of coeliac disease prior to the diagnosis of lymphoma was 21.2 years, and of carcinoma of the gastrointestinal tract 38.5 years. A gluten-free diet appeared to decrease the risk of malignant complication.

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  • Cited by (0)

    1

    From the Nutritional and Intestinal Unit, General Hospital, Birmingham, and the Departments of Pathology and Social Medicine, Birmingham University, Birmingham, England.

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