Abstract
Background
Split-dose bowel preparations for colonoscopy have superior effectiveness compared with giving all the preparation the evening before colonoscopy. Some physicians believe that split-dose preparations would be unpopular with patients scheduled for early morning colonoscopies.
Aims
To determine the willingness of potential patients to undergo split-dose bowel preparation for colonoscopy and the actual adherence of colonoscopy patients to split-dose instructions.
Methods
We performed a survey of esophagogastroduodenoscopy patients and drivers of colonoscopy patients asking whether they would accept split-dose preparations for early morning colonoscopy appointments. We also asked colonoscopy patients scheduled in the early morning if they had complied with the written preparation instructions.
Results
Of the 300 individuals surveyed, the majority (85%) stated they would be willing to get up during the night to take the second dose of preparation. Of 107 colonoscopy patients with early morning appointments, 78% actually got up during the night to take the second dose of preparation.
Conclusions
Acceptance of and compliance with split-dose bowel preparations is high and should not be a deterrent to prescribing split-dose preparations for colonoscopy.
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References
Harewood GC, Sharma VK, de Garmo P. Impact of colonoscopy preparation quality on detection of suspected colonic neoplasia. Gastrointest Endosc. 2003;58:76–79.
Parra-Blanco A, Nicolas-Perez D, Gimeno-Garcia A, et al. The timing of bowel preparation before colonoscopy determines the quality of cleansing, and is a significant factor contributing to the detection of flat lesions: a randomized study. World J Gastroenterol. 2006;12:6161–6166.
Froehlich F, Wietlisbach V, Gonvers JJ, Burnand B, Vader JP. Impact of colonic cleansing on quality and diagnostic yield of colonoscopy: the European Panel of Appropriateness of Gastrointestinal Endoscopy European multicenter study. Gastrointest Endosc. 2005;61:378–384.
Rex DK, Imperiale TF, Latinovich DR, Bratcher LL. Impact of bowel preparation on efficiency and cost of colonoscopy. Am J Gastroenterol. 2002;97:1696–1700.
Rostom A, Jolicoeur E, Dube C, et al. A randomized prospective trial comparing different regimens of oral sodium phosphate and polyethylene glycol-based lavage solution in the preparation of patients for colonoscopy. Gastrointest Endosc. 2006;64:544–552.
Aoun E, Abdul-Baki H, Azar C, et al. A randomized single-blind trial of split-dose PEG-electrolyte solution without dietary restriction compared with whole dose PEG-electrolyte solution with dietary restriction for colonoscopy preparation. Gastrointest Endosc. 2005;62:213–218.
Park JS, Sohn CI, Hwang SJ, et al. Quality and effect of single dose versus split dose of polyethylene glycol bowel preparation for early-morning colonoscopy. Endoscopy. 2007;39:616–619.
Church JM. Effectiveness of polyethylene glycol antegrade gut lavage bowel preparation for colonoscopy—timing is the key! Dis Colon Rectum. 1998;41:1223–1225.
El Sayed AM, Kanafani ZA, Mourad FH, et al. A randomized single-blind trial of whole versus split-dose polyethylene glycol-electrolyte solution for colonoscopy preparation. Gastrointest Endosc. 2003;58:36–40.
Frommer D. Cleansing ability and tolerance of three bowel preparations for colonoscopy. Dis Colon Rectum. 1997;40:100–104.
Abdul-Baki H, Hashash JG, Elhajj II, et al. A randomized, controlled, double-blind trial of the adjunct use of tegaserod in whole-dose or split-dose polyethylene glycol electrolyte solution for colonoscopy preparation. Gastrointest Endosc. 2008;68:294–300. quiz 334, 336.
Chiu HM, Lin JT, Wang HP, Lee YC, Wu MS. The impact of colon preparation timing on colonoscopic detection of colorectal neoplasms—a prospective endoscopist-blinded randomized trial. Am J Gastroenterol. 2006;101:2719–2725.
Gupta T, Mandot A, Desai D, Abraham P, Joshi A, Shah S. Comparison of two schedules (previous evening versus same morning) of bowel preparation for colonoscopy. Endoscopy. 2007;39:706–709.
Gagovic V, Rex DK. Gastroenterologists’ patient instructions for oral sodium phosphate solution for colonoscopy preparation: a survey among gastroenterologists in the State of Indiana. J Clin Gastroenterol 2008.
Practice guidelines for preoperative fasting and the use of pharmacologic agents to reduce the risk of pulmonary aspiration. Application to healthy patients undergoing elective procedures: a report by the American Society of Anesthesiologist Task Force on Preoperative Fasting. Anesthesiology. 1999;90:896–905.
Lin O, Schembre DB. Are split bowel preparation regimens practical for morning colonscopies? Implications of the new American College of gastroenterology colon cancer screening guidelines for real world clinical practice. Am J Gastroenterol (in press).
Rostom A, Jolicoeur E. Validation of a new scale for the assessment of bowel preparation quality. Gastrointest Endosc. 2004;59:482–486.
Rex DK, Johnson DA, Anderson JC, Schoenfeld PS, Burke CA, Inadomi JM. American College of Gastroenterology guidelines for colorectal cancer screening 2008. Am J Gastroenterol. 2009;104:739–750.
Khan M, Wasiuddin N, Brown MD. Patient acceptance, convenience and efficacy of one-day versus two-day colonoscopy bowel preparation. Gastrointest Endosc. 2008;67:AB246.
Acknowledgments
Douglas K. Rex—Braintree Laboratories—Research Support; C.B. Fleet Co.—Consultant. The other authors have no conflicts of interest.
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Appendix
Appendix
Willingness to undergo split-dose bowel preparation survey
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1.
Have you ever had a colonoscopy? Yes _____ No ______
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2.
Age _____ Gender _____ Having EGD _____ Driver _____
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3.
Recent studies have proven that taking one half of the prescribed bowel laxative preparation for colonoscopy on the same day as the colonoscopy (usually about 4–5 h prior to the scheduled time) improves the quality of the bowel preparation. The alternative is to take the entire prep the night before. If the colon is well cleaned there are several benefits: (1) any polyps you have are more likely to be found by the doctor; (2) your doctor is more likely to recommend a long period of time (for example 5–10 years) before you need a repeat colonoscopy. Given this information, and assuming that you are scheduled at 7 or 8:00 a.m. for a colonoscopy, please answer this question:
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1.
Would you be willing to get up at 2 or 3:00 a.m. to take the second half of the preparation?
Yes _____ No _____
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2.
Assuming that you take the second half of the preparation several hours before you are scheduled, which appointment time would you prefer?
Early morning (7–8 a.m.) _____
Mid morning (9–10 a.m.) _____
Late morning (11 a.m.–noon) _____
Early afternoon (1–2 p.m.) _____
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Unger, R.Z., Amstutz, S.P., Seo, D.H. et al. Willingness to Undergo Split-Dose Bowel Preparation for Colonoscopy and Compliance with Split-Dose Instructions. Dig Dis Sci 55, 2030–2034 (2010). https://doi.org/10.1007/s10620-009-1092-x
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DOI: https://doi.org/10.1007/s10620-009-1092-x