Observed and expected deaths for coeliac disease patients with results stratified by year of diagnosis*
| Diagnosis before 1 January 1990* (total person-years=4306.2) | Diagnosis between 1 January 1990 and 31 December 1999 (total person-years=7324.2) | Diagnosis after 1 January 2000 (total person-years=12 324.5 | |||||||
| Observed | Expected | SMR (95% CI) | Observed | Expected | SMR (95% CI) | Observed | Expected | SMR (95% CI) | |
| All deaths | 58 | 58.5 | 0.99 (0.75 to 1.28) | 109 | 48.8 | 2.23 (1.83 to 2.70) | 117 | 73.1 | 1.60 (1.32 to 1.92) |
| Cardiovascular (I00–I99) | 19 | 23.2 | 0.82 (0.49 to 1.28) | 42 | 19.4 | 2.17 (1.56 to 2.93) | 27 | 29.1 | 0.93 (0.61 to 1.35) |
| Malignancy (C00–D48) | 16 | 17.6 | 0.91 (0.52 to 1.48) | 33 | 14.6 | 2.25 (1.55 to 3.16) | 34 | 22.0 | 1.55 (1.07 to 2.16) |
| Respiratory (J00–J99) | 9 | 6.7 | 1.34 (0.61 to 2.54) | 14 | 5.6 | 2.50 (1.36 to 4.19) | 24 | 8.4 | 2.85 (1.83 to 4.24) |
| Digestive (K00–K93) | 5 | 2.4 | 2.09 (0.68 to 4.87) | 12 | 2.0 | 6.01 (3.10 to 10.49) | 5 | 3.0 | 1.67 (0.54 to 3.89) |
*Excluding prevalent cases diagnosed before 1 January 1978. A total of 27 deaths in 5163 person-years of follow-up occurred among prevalent cases.
†Eight deaths from accidents and suicide among incident cases are not included in the above table due to small numbers in each diagnosis period.
SMR, standardised mortality ratio.