Table 3

Dose optimisation algorithm

FCP levelDL <2.5DL >2.5DL 4–6.5DL >6.5
>250Increase dose by 50 mg every 4 weeks until DL >4Increase dose by 50 mg every 4 weeks until DL >4Maintain doseMaintain dose
50–250Increase dose by 50 mg every 4 weeks until DL >2.5Maintain doseMaintain dose*Reduce dose by 50 mg
<50Maintain doseMaintain doseReduce dose*Reduce dose by 50 mg
  • DL, drug levels; FCP, faecal calprotectin.