Laboratory features of liver biopsy group (n=46)
| Laboratory features | Non-established PBC (n=22) | Overlap (n=12) | PBC (n=12) | p* |
| ALT mean (median, range) IU/L | 115 (62, 15–554) | 332 (186, 24–1540) | 65 (64, 27–133) | 0.037†‡ |
| AST mean (median, range) IU/L | 121 (70, 19–720) | 287 (185, 29–960) | 57 (54, 29–85) | 0.002†‡ |
| AP mean (median, range) IU/L | 185 (160, 72–428) | 638 (688, 94–1357) | 244 (180, 93–679) | 0.001†‡ |
| Total bilirubin mean (median, range) | 2.136 (0.95, 0.2–13.5) | 5.05 (4.25, 0.6–19.5) | 0.692 (0.55, 0.2–1.9) | 0.001†‡ |
| Platelet count mean ×109 (median, range) | 214 (199,53–523) | 311(189, 60-443) | 255 (245, 72–598) | 0.397 |
| Albumin mean (median, range) | 3.8 (4, 1.9–4.9) | 3.4 (3.5, 2.2–4.3) | 3.8 (3.9, 2.6–4.3) | 0.244 |
*Independent sample Kruskal-Wallis test.
†Mann-Whitney test significant for non-established PBC versus overlap.
‡Mann-Whitney test significant for overlap versus PBC.
§Mann-Whitney test significant for Non-established PBC versus PBC.
ALT, alanine aminotransferase; AP, alkaline phosphatase; AST, aspartate aminotransferase; PBC, primary biliary cholangitis.