Univariate (n=1880) | Multivariate (n=922) | |||||
---|---|---|---|---|---|---|
HR | 95% CI | p Value | HR | 95% CI | p Value | |
Male sex (n=1880) | 1.04 | 0.90 to 1.20 | 0.61 | 1.01 | 0.82 to 1.24 | 0.94 |
Age at HCC diagnosis (n=1880) | 1.01 | 1.01 to 1.02 | <0.001 | 1.02 | 1.01 to 1.03 | <0.001 |
Non-surgical first treatment (n=1874) | 0.38 | 0.33 to 0.43 | <0.001 | 0.41 | 0.34 to 0.50 | <0.001 |
Surgical first treatment (n=1874) | 0.20 | 0.16 to 0.25 | <0.001 | 0.24 | 0.16 to 0.35 | <0.001 |
No screening (n=1132) | 1.98 | 1.69 to 2.33 | <0.001 | 1.48 | 1.23 to 1.79 | <0.001 |
Cirrhosis (n=1880) | 1.10 | 0.93 to 1.28 | 0.27 | 1.02 | 0.73 to 1.44 | 0.89 |
Milan (n=1880) | 0.51 | 0.45 to 0.57 | <0.001 | 0.54 | 0.44 to 0.65 | <0.001 |
MELD (n=1458) | 1.06 | 1.05 to 1.07 | <0.001 | 1.06 | 1.05 to 1.08 | <0.001 |
Asian (n=1870) | 0.78 | 0.69 to 0.88 | <0.001 | |||
OLT (n=1868) | 0.21 | 0.17 to 0.27 | <0.001 | |||
CPT (n=1446) | 1.52 | 1.39 to 1.67 | <0.001 | |||
BCLC (n=1003) | 1.79 | 1.62 to 1.98 | <0.001 |
Bolded p values indicate significant differences (p<0.05).
BCLC, Barcelona Clinic Liver Cancer staging classification; CPT, Child-Pugh-Turcotte score; HCC, hepatocellular carcinoma; MELD, Model for End-Stage Liver Disease; OLT, orthotopic liver transplantation.