Characteristics of boys born in Denmark between 1979–2009 and 1996–2009 according to maternal IBD status, N=966 038
| Maternal Crohn's disease (n=1685) | Maternal ulcerative colitis (n=3003) | No Maternal IBD (n=961 350) | |
|---|---|---|---|
| Characteristics | n (%) | n (%) | n (%) |
| Number of hypospadias | |||
| Overall | 15 (0.9) | 21 (0.7) | 6112 (0.6) |
| Diagnosed within the first 6 months after birth | 9 (0.5) | 6 (0.2) | 3512 (0.4) |
| Mother's age at delivery (years) | |||
| <25 | 206 (12.2) | 290 (9.7) | 198 295 (20.6) |
| 25–29 | 618 (36.7) | 1035 (34.5) | 360 712 (37.5) |
| ≥30 | 861 (51.1) | 1678 (55.9) | 402 343 (41.9) |
| Birth order | |||
| 1 | 804 (47.7) | 1278 (42.6) | 432 383 (45.0) |
| ≥2 | 881 (52.3) | 1725 (57.4) | 528 967 (55.0) |
| Maternal preeclampsia during pregnancy | |||
| Yes | 55 (3.3) | 74 (2.5) | 28 364 (3.0) |
| Maternal epilepsy during pregnancy | |||
| Yes | 17 (1.0) | 21 (0.7) | 7691 (0.8) |
| Maternal diabetes during pregnancy | |||
| Yes | 13 (0.8) | 19 (0.6) | 4750 (0.5) |
| (N=1311) | (N=2034) | (N=454 492) | |
| Maternal smoking during pregnancy* | |||
| No | 931 (71.0) | 1692 (83.2) | 350 728 (77.2) |
| ≤10 cigarettes/day | 229 (17.5) | 201 (10.1) | 65 301 (14.4) |
| >10 cigarettes/day | 100 (7.6) | 55 (2.7) | 21 708 (4.8) |
| Missing | 51 (3.9) | 81 (4.0) | 16 755 (3.7) |
| Maternal use of oral contraceptives before pregnancy* | |||
| Yes | 133 (10.1) | 202 (9.9) | 40 960 (9.0) |
| Maternal use of ovulation-inducing drugs* | |||
| Yes | 107 (8.2) | 183 (9.0) | 27 333 (6.0) |
| Maternal use of antidiabetics during pregnancy* | |||
| Yes | 9 (0.7) | 25 (1.2) | 4148 (0.9) |
| Maternal use of antiepileptics during pregnancy* | |||
| Yes | 8 (0.6) | 9 (0.4) | 2229 (0.5) |
*Children born from 1996 onwards, N=457,837.
IBD, inflammatory bowel disease.