Demographic and clinical values, by sex
| Demographic and clinical values | Overall cohort (n=1886) | Females (n=437) | Males (n=1449) | p Value |
|---|---|---|---|---|
| Ethnicity (n=1870) | 0.05 | |||
| Asian | 792 (42.4%) | 192 (44.3%) | 600 (41.8%) | |
| White | 726 (38.8%) | 150 (34.6%) | 576 (40.1%) | |
| Hispanic | 292 (15.6%) | 69 (15.9%) | 223 (15.5%) | |
| Black | 31 (1.7%) | 12 (2.8%) | 19 (1.3%) | |
| Other | 29 (1.6%) | 10 (2.3%) | 19 (1.3%) | |
| Aetiology | ||||
| Age at HCC diagnosis (n=1886) | 60.8±11.1 | 64.0±11.6 | 59.9±10.7 | <0.0001 |
| BMI (n=744) | 26.5±5.7 | 26.1±6.3 | 26.6±5.6 | 0.30 |
| History of alcohol use (n=1838) | 1040 (56.6%) | 150 (35.1%) | 890 (63.2%) | <0.001 |
| History of tobacco use (n=1854) | 954 (51.5%) | 132 (31.0%) | 822 (57.7%) | <0.001 |
| HCV (n=1886) | 914 (48.5%) | 224 (51.3%) | 690 (47.6%) | 0.18 |
| Asian HCV (n=789) | 271 (34.4%) | 85 (44.5%) | 186 (31.1%) | 0.001 |
| Non-Asian HCV (n=1097) | 642 (58.6%) | 139 (56.5%) | 503 (59.3%) | 0.45 |
| HBV (n=1886) | 446 (23.7%) | 90 (20.6%) | 356 (24.6%) | 0.09 |
| Asian HBV (n=789) | 415 (52.6%) | 83 (43.5%) | 332 (55.5%) | 0.004 |
| Non-Asian HBV (n=1097) | 31 (2.8%) | 7 (2.9%) | 24 (2.8%) | 0.98 |
| Alcoholic liver disease (n=1781) | 114 (6.4%) | 14 (3.5%) | 100 (7.3%) | 0.006 |
| Co-morbidities | ||||
| HTN (n=1666) | 821 (49.3%) | 200 (51.8%) | 621 (48.5%) | 0.26 |
| Hyperlipidaemia (n=1664) | 209 (12.6%) | 46 (11.9%) | 163 (12.8%) | 0.66 |
| DM (n=1670) | 520 (31.1%) | 118 (30.6%) | 402 (31.3%) | 0.78 |
| CAD (n=1665) | 114 (6.9%) | 24 (6.2%) | 90 (7.0%) | 0.58 |
| COPD (n=1666) | 57 (3.4%) | 16 (4.2%) | 41 (3.2%) | 0.37 |
| Advanced liver disease | ||||
| Cirrhosis (n=1886) | 1572 (83.4%) | 366 (83.8%) | 1206 (83.2%) | 0.80 |
| Ascites (n=1869) | 674 (36.1%) | 167 (38.6%) | 507 (35.3%) | 0.20 |
| Encephalopathy (n=1864) | 354 (19.0%) | 89 (20.7%) | 265 (18.5%) | 0.32 |
| GI bleed (n=1325) | 332 (25.1%) | 68 (21.4%) | 264 (26.2%) | 0.08 |
| Decompensation (n=1886) | 862 (45.7%) | 194 (44.4%) | 668 (46.1%) | 0.53 |
Bolded p values indicate significant difference (p<0.05).
ALB, albumin; ALT, alanine aminotransferase; AST, aspartate aminotransferase; BMI, body mass index; CAD, coronary artery disease; COPD, chronic obstructive pulmonary disease; CR, creatinine; DM, diabetes mellitus; GI, gastrointestinal; HCC, hepatocellular carcinoma; HCV, chronic hepatitis C; HBV, chronic hepatitis B; HGB, haemoglobin; HTN, hypertension; INR, international normalised ratio; PLT, platelet; TB, tuberculosis.