Table 3

Multivariate logistic analysis

 Rapid viral responseUndetectable or VL ≤15 UI
OR95% CIp ValueOR95% CIp Value
Treatment initiation (Season A vs Season B)2.031.27 to 3.250.0031.931.14 to 3.290.014
Type of therapy (lead-in no vs yes)23.7010.66 to 52.69<0.000190.146.54 to 174.6<0.0001
HCV RNA (≤600 000 vs >600 000 IU/mL)2.141.29 to 3.550.0034.662.36 to 9.17<0.0001
IL-28 polymorphism (CC vs no CC)1.941.14 to 3.300.0142.241.17 to 4.290.015
Naïve vs experienced1.550.91 to 2.630.100.740.41 to 1.310.30
Genotype (1b vs 1a)1.320.73 to 2.400.350.710.37 to 1.360.30
Diabetes mellitus (no vs yes)1.280.63 to 2.610.491.420.66 to 3.050.36
Age (≥50 vs <50 years)0.920.55 to 1.520.751.010.58 to 1.780.95
Fibrosis (≥F3 vs <F3)0.920.51 to 1.660.791.630.80 to 3.300.17
  • HCV, hepatitis C virus; VL, viral load.