Patient treatment histories and documented drug resistance mutation testing results
| ETV–TDF combination arm | ETV monotherapy arm | ||
|---|---|---|---|
| Previous treatment profile | Patients, n | Previous treatment profile | Patients, n |
| LAM, ADV, ETV | 9 | Naive | 16 |
| LAM, ETV | 7 | ADV Mono | 6 |
| ETV Mono | 5 | LAM, ADV | 4 |
| LAM, ADV | 4 | LAM, ADV, INF | 3 |
| LAM, ADV, INF | 3 | LAM Mono | 2 |
| 1 | LAM, FAM | 1 | |
| LAM, ADV, FAM | 1 | LAM, INF | 1 |
| LAM, ADV, ETV, TBD | 1 | LAM, ADV, TDF, INF | 1 |
| LAM, ETV, INF | 1 | TBD Mono | 1 |
| ETV, INF | 1 | ||
| ETV, ADV | 1 | ||
| ADV, FTC | 1 | ||
| Mutation | ETV–TDF combination arm | ETV monotherapy arm |
|---|---|---|
| 80 | 1 | 0 |
| 81 | 2 | 0 |
| 173 | 1 | 0 |
| 180 | 13 | 2 |
| 181 | 4 | 0 |
| 204 | 7 | 3 |
| 236 | 6 | 0 |
| 1762 | 10 | 6 |
| BCP | 11 | 8 |
| Precore | 7 | 13 |
ADV, adevofir dipivoxil; BCP, basal core promoter; ETV, entecavir; FAM, famciclovir; FTC, emtricitabine; INF, interferon; LAM, lamuvidine; Mono, monotherapy; TBD, telbuvidine; TDF, tenofovir disoproxil fumarate.