Predictors in colectomy
| Colectomy | Non-colectomy | p Value | |
|---|---|---|---|
| (n=6) | (n=23) | ||
| Age at diagnosis of severe UC (median (range)) (years) | 49.5 (20–64) | 33 (19–69) | 0.153 |
| Disease duration prior to the induction therapy (median (range)) (months) | 50 (4–348) | 34 (2–157) | 0.590 |
| Gender | 0.494 | ||
| Male | 3 | 15 | |
| Female | 3 | 8 | |
| Partial Mayo score (median (range)) | 8.5 (8–9) | 9 (8–9) | 0.936 |
| Endoscopic Mayo score (median (range)) | 3 (2–3) | 3 (3–3) | 0.893 |
| Disease extent | 0.160 | ||
| Extensive | 6 | 17 | |
| Left sided | 0 | 6 | |
| Laboratory examination (mean±SD (range)) (mg/dL) | |||
| C reactive protein | 8.1±9.8 (1.2–27.1) | 6.8±6.5 (0.1–18.7) | 0.893 |
| Haemoglobin | 9.7±1.5 (7.5–11.8) | 10.4±1.8 (7.9–13.1) | 0.518 |
| Albumin | 2.7±0.6 (1.7±3.4) | 3.0±0.6 (1.8–4.0) | 0.318 |
| Daily dosage of corticosteroid prior to TAC or IFX (median (range)) (mg/day) | 17.5 (0–60) | 7.5 (0–60) | 0.647 |
| Positive rate of CMV reactivation (percentage (positive/all)) (%) | 83.3 (5/6) | 34.8 (8/23) | 0.033 |
| Copy number of CMV-DNA in patients with CMV reactivation (median (range)) (copies/μg) | 975 (320–1400) | 1300 (390–12 000) | 0.445 |
Numbers of patients are shown unless specified.
CMV, cytomegalovirus; IFX, infliximab; TAC, tacrolimus; UC, ulcerative colitis.